Smoking is a major health risk in the EU, and there is a need to improve tobacco cessation methods. ‘Sick Of Smoking’ is a novel method for tobacco cessation (TC), consisting of a unique form of aversive conditioning that uses three 5-minute virtual reality (VR) sessions to rapidly induce a powerful and long-lasting aversion to the taste and smell of cigarettes. Nausea is induced while the participant consumes their tobacco after a period of abstinence that was as long as they can comfortably manage. This combination triggers the ‘Garcia effect’, a powerful and highly conserved biological mechanism that creates a taste aversion to the taste and smell of the participants tobacco product (cigarettes, snus or vapes for example).