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3rd ENSP-CNPT International Conference on Tobacco Control
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The official journal of ENSP, the European Network for Smoking and Tobacco Prevention
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Journal development is co-funded by the 3rd Health Programme of the European Commission
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RESEARCH PAPER
Satisfactory throat-hit is needed to switch from tobacco to e-cigarettes: a lesson from an e-liquid blind test
| 1 | École d'ingénieurs ECE Paris, France |
| 2 | University College London, London, United Kingdom |
| 3 | Tabacologie, Pitié-Salpêtrière, APHP, Paris France |
| 4 | Paris Sans Tabac, Paris, France |
CORRESPONDING AUTHOR
Bertrand Dautzenberg
Service Pneumologie et Réanimation GHU Pitié-Salpêtrière-Charles Foix APHP 47-81 Bd de l’Hôpital 75651 Paris cedex 13 Bureau +33 1 42 17 67 70 (72)
Service Pneumologie et Réanimation GHU Pitié-Salpêtrière-Charles Foix APHP 47-81 Bd de l’Hôpital 75651 Paris cedex 13 Bureau +33 1 42 17 67 70 (72)
Submission date: 2015-10-29
Final revision date: 2016-04-21
Acceptance date: 2016-04-27
Publication date: 2016-04-27
Tob. Prev. Cessation 2016;2(April):62
KEYWORDS
TOPICS
ABSTRACT
Introduction:
The aim of the study was to confirm or reject the hypothesis that variation in throat-hit depends on the nicotine concentration and the voltage applied to the resistance. A secondary aim was to assess the influence of throat-hit on the willingness of subjects to switch from tobacco to e-cigarette use.
Methods:
In this experimental blind test participants were 35 students (aged 22.0±7.7), current smokers, who tested five e-liquids with a nicotine concentration between 0 to 18mg/mL, at 3.5 or 4.5 volts (at 1.8Ω) powered by EGO type e-cigarettes . After describing their smoking habits (heaviness smoking index (HSI), and signing consent, participants smoked 1 puff every 5 minutes, inhaling for 3 seconds, for each of the 10 conditions and rated their subjective experience.
Results:
Analysis of the 350 puffs from the 35 smokers,indicated a learning process of 5 puffs. Within this population a nicotine concentration of 12.6mg/mL combined to 3.5volts and 10.9mg/mL combined to 4.5volts was associated with OTH. Our results indicated a link between tobacco dependence and nicotine concentration of the e-liquid that provided an optimal throat-hit (OTH), with an +1.6mg/mL increase in nicotine content needed for the OTH for each one point increase in HSI. A link between the desire to switch from tobacco to e-cigarettes and the score of throat-hit was identified (r2=0.94). This desire is <1/10 when throat-hit is unpleasant (score 0-3) and exceeds 7/10 when throat-hit is optimal (score 7-10).
Conclusions:
The present data justify the need to further develop e-cigarettes so that an optimal OTH is identified quickly. Further research is needed to confirm the above results in other populations and to assess the specific influence of flavour on throat hit.
The aim of the study was to confirm or reject the hypothesis that variation in throat-hit depends on the nicotine concentration and the voltage applied to the resistance. A secondary aim was to assess the influence of throat-hit on the willingness of subjects to switch from tobacco to e-cigarette use.
Methods:
In this experimental blind test participants were 35 students (aged 22.0±7.7), current smokers, who tested five e-liquids with a nicotine concentration between 0 to 18mg/mL, at 3.5 or 4.5 volts (at 1.8Ω) powered by EGO type e-cigarettes . After describing their smoking habits (heaviness smoking index (HSI), and signing consent, participants smoked 1 puff every 5 minutes, inhaling for 3 seconds, for each of the 10 conditions and rated their subjective experience.
Results:
Analysis of the 350 puffs from the 35 smokers,indicated a learning process of 5 puffs. Within this population a nicotine concentration of 12.6mg/mL combined to 3.5volts and 10.9mg/mL combined to 4.5volts was associated with OTH. Our results indicated a link between tobacco dependence and nicotine concentration of the e-liquid that provided an optimal throat-hit (OTH), with an +1.6mg/mL increase in nicotine content needed for the OTH for each one point increase in HSI. A link between the desire to switch from tobacco to e-cigarettes and the score of throat-hit was identified (r2=0.94). This desire is <1/10 when throat-hit is unpleasant (score 0-3) and exceeds 7/10 when throat-hit is optimal (score 7-10).
Conclusions:
The present data justify the need to further develop e-cigarettes so that an optimal OTH is identified quickly. Further research is needed to confirm the above results in other populations and to assess the specific influence of flavour on throat hit.
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CITATIONS (4):
1.
The Importance of Conditioned Stimuli in Cigarette and E-Cigarette Craving Reduction by E-Cigarettes
Martijn Van Heel, Dinska Van Gucht, Koen Vanbrabant, Frank Baeyens
International Journal of Environmental Research and Public Health
Martijn Van Heel, Dinska Van Gucht, Koen Vanbrabant, Frank Baeyens
International Journal of Environmental Research and Public Health
2.
Early Subjective Sensory Experiences with “Cigalike” E-cigarettes Among African American Menthol Smokers: A Qualitative Study
Sabrina L Smiley, Teresa DeAtley, Leslie F Rubin, Emily Harvey, Elexis C Kierstead, Monica Webb Hooper, Raymond S Niaura, David B Abrams, Jennifer L Pearson
Nicotine & Tobacco Research
Sabrina L Smiley, Teresa DeAtley, Leslie F Rubin, Emily Harvey, Elexis C Kierstead, Monica Webb Hooper, Raymond S Niaura, David B Abrams, Jennifer L Pearson
Nicotine & Tobacco Research
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L’usage d’e-cigarette chez les usagers de cannabis et les polyconsommateurs : étude de cohorte
S. Kinouani, R. Tsopra, S. Maurice, B. Soen, N. Germemont, E. Langlois, B. Gay
Revue des Maladies Respiratoires
S. Kinouani, R. Tsopra, S. Maurice, B. Soen, N. Germemont, E. Langlois, B. Gay
Revue des Maladies Respiratoires
4.
Cigarette électronique chez les patients fumeurs présentant une pathologie psychotique. Revue de la littérature
M. Underner, J. Perriot, G. Brousse, Chazeron de, A. Schmitt, G. Peiffer, R. Afshari, S. Ebrahimighavam, N. Jaafari
L'Encéphale
M. Underner, J. Perriot, G. Brousse, Chazeron de, A. Schmitt, G. Peiffer, R. Afshari, S. Ebrahimighavam, N. Jaafari
L'Encéphale
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