Introduction:
The main objective of this work is to define the key objectives and actions of the smoke-free spaces strategic line of the Updated Comprehensive Tobacco Action Plan for Andalusia (PITA).

Material and Methods:
A coordinating team was established to define the main pillars of the Comprehensive Plan for smoke-free spaces in Andalusia. The team included professionals from the General Directorate of Public Health and Pharmaceutical Regulation, the current PITA Team, and the The Andalusian School of Public Health. The methodology employed in the document was executed in a three-phase approach: 1) in-person meetings with working groups, 2) online analysis and improvement of previous documents, 3) integration of different parts of the document by the coordinating group.

Conclusions:
This work provided a comprehensive strategic line for smoke-free spaces in Andalusia. The plan included key objectives and actions in order to protect the Andalusian population from environmental tobacco smoke.