Smoking cessation in female lung cancer patients- the need for a personalized approach
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University of Medicine and Pharmacy "Grigore T. Popa", Iasi, Romania
Clinical Hospital of Pulmonary Diseases Iasi, Romania
Publication date: 2019-03-26
Tob. Prev. Cessation 2019;5(Supplement):A142
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Actually, there is a major deficiency worldwide in smoking prevention and cessation programs addressing women. Lung cancer is the most common cause of death from cancer worldwide; it is the third deaths cause in Europe after breast and prostate cancer. Lung cancer has different characteristics in women and in men; in women that smoke adenocarcinoma is more common. There is a difference in the behavior, prognosis and response to treatment in non-small cell lung cancer by sex and by hormonal status. Quitting smoking was associated with a reduction in mortality. Women are affected differently than men by tobacco consumption: the fear of weight gain is higher, smoking is practiced as an antidote to negative feelings or as a "time-out ", the socio-sensorial context has a greater impact on the addiction of women than nicotine, suggesting that the use of nicotine substitution therapy will have a low impact on this category of smokers. Women also give up smoking harder due to: a differentiated response to nicotine, lack of social support, depression and a specific hormonal configuration. More smoking relapses are described in women; also a differentiated correlation with tobacco exposure biomarkers 1. That`s why there is a great need for a more personalized approach in this field, focused on the specific aspects of female tobacco consumption and cessation and on characteristics of lung cancer in females.
Trofor A, Petris O, Trofor L, Man MA, Filipeanu D, Miron R. Biochemistry in assessing tobacco exposure - smokers versus non-smokers - correlations with clinical practice. Revista de Chimie. 2017;68(5):1002-1006.
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