Development and Evaluation of the Effectiveness of Vernonia cinerea (VC) Cookies for Smoking Cessation
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College of Medicine and Public Health, Ubon Ratchathani University, Az-Zarqa, Jordan
Leukanharn Warinchumrab School
Faculty of Nursing, Phayao University, Thailand
Rajamongkol Technical College, Surin, Thailand
Anun Chaikoolvatana   

College of Medicine and Public Health, Ubon Ratchathani University, Az-Zarqa, Jordan, Department of Pharmacy, Ubon Ratchathani University, 34190 Warinchumrab, Ubon Ratchathani, Thailand
Submission date: 2017-05-09
Acceptance date: 2017-05-09
Publication date: 2017-05-25
Tob. Prev. Cessation 2017;3(May Supplement):45
Vernonia cineea (VC) has been known as a herbal medicine for long time. Recently, it was used for smoking cessation. The study investigated the effectiveness of VC cookies, side effects and satisfaction of its product.

Material and Methods:
The study was designed as a quasi-experimental study. VC cookies were developed. A total of 63 subjects (high school students) were selected with 75% of them were current smokers. Each subject was selected into the VC and non-VC (Control) group. The study (VC) group received 5 VC pieces a day, whereas the control (non VC) group received 5 plain cookies per day for six months. All data were collected via a questionnaire paper. The descriptive and analytical analyses including Chi-square (χ2) test and Mann-Whitney –test, and adjusted odds ratio and 95% confidence interval were used.

The percentages of quitters in the study (VC) group were significantly higher than those in the control (non VC) group throughout 6 month periods (p <.001, .001, and <.001, consecutively). Additionally, average carbon-monoxide (CO) levels of the VC group from 1-month to 6-month periods were significantly different compared to the non VC group (p <.001). Common side effects of VC found, including; mouth and throat, high blood pressure. Finally, there was a significant relationship between VC cookies and cessation behavior (95% CI: 1.65, 251.60).

Vernonia cinerea (VC) has been shown the high percentages of continuous abstinence rates with the decrease of CO levels compared to non VC group. Some minor side effects and favorable feedback of VC cookies were also reported. Further investigations of the efficacy and safety of VC products need to be addressed.

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