BACKGROUND-AIM:
Electronic cigarette use among adolescents is a growing public health concern, with high prevalence rates observed in Cyprus and across Europe. Despite this, there is a lack of targeted, evidence-based cessation interventions specifically designed for youth. The aim of the present project is to develop and evaluate FlexiQuit Vaping, an ACT-based digital therapeutic delivered via a mobile application, designed to support vaping cessation among adolescents with varying levels of readiness to quit.

METHODS:
The intervention is delivered through a mobile application incorporating Acceptance and Commitment Therapy (ACT), gamification, and an avatar-guided experience. The program consists of six interactive sessions focusing on values clarification, trigger awareness, cognitive defusion, acceptance, and relapse prevention. The intervention will be co-developed with students and experts to ensure usability and engagement. Its effectiveness will be evaluated through a randomized controlled trial (RCT), comparing the intervention to a waitlist control group. Primary outcomes include readiness to quit, quit attempts, and 30-day abstinence at 6 months post-randomization.

RESULTS:
The project is currently under development. It is expected that the intervention will demonstrate high usability, engagement, and acceptability among adolescents. Based on previous research on ACT-based digital interventions, we anticipate improvements in psychological flexibility, increased quit attempts, and higher abstinence rates compared to control conditions.

CONCLUSIONS:
FlexiQuit Vaping represents an innovative, theory-driven digital intervention addressing a critical gap in youth vaping cessation. If proven effective, it has the potential to be scaled within school settings, contributing to public health efforts toward reducing nicotine use and supporting the goal of a smoke-free generation. Youth tobacco prevention